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Vol. 193, Issue 10, October 2015, pp. 57-62




Advanced Controlled Cryogenic Ablation Using Ultrasonic Sensing System

* Assaf Sharon, Gabor Kosa
Robots and BioMedical Micro Systems (RBM2S) research laboratory, School of Mechanical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv, Israel
Tel.: + 972523404144, fax: 972-3-6407334

* E-mail: assaf.a1@gmil.com


Received: 31 August 2015 /Accepted: 5 October 2015 /Published: 30 October 2015

Digital Sensors and Sensor Sysstems


Abstract: Cryoablation process is one of the methods for treating various tissue abnormities. Cryoablation devices are mostly minimally invasive and are used in open loop control, monitored by additional imaging devices. In this study, we monitor the growth of the ablated area by using a miniature ultrasonic transducer that is collocated with the tip of the cryogenic device. The 20 MHz ultrasonic sensor is capable of measuring the size of the ice sphere that is created in front of the needle. In addition to real time monitoring of the ablation process, the ultrasonic sensor will be able to determine the local thickness of the tissue prior to the treatment (thus enabling the setting of the power of the ablation treatment). The combined device will shorten the ablation treatment and will eliminate the need for additional ablation treatments or monitoring devices. The proof of concept was done in water, ultrasonic gel and muscle tissue. In the experiments we found that, in the frequency domain one can identify at 10-12 MHz the increase of the intensity of the returned echo in the ice and the decrease of the signal after the ice-tissue boundary. One can correlate the increase of the intensity with the growth of the ice sphere.


Keywords: Cryogenic, Ablation, Control, Ultrasound, Piezo, Ice.


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