bullet Sensors & Transducers Journal

    (ISSN: 2306-8515, e-ISSN 1726-5479)


   About this Journal

   Information for Authors

   Editorial Board

   Editorial Calendar

   Current Issue

   Browse Journal

S&T journal's cover

Submit Press Release

Submit White Paper

25 Top Downloaded Articles (2007-2012)


Contact Us





Vol. 28, Special Issue, April-May 2018, pp. 7-12




Molecularly Imprinted Polymer Sensing Layer for Tetracycline Chemical Sensor
Based on Piezoelectric Quartz Crystal Transducer

* Benilda S. EBARVIA and Isaiah E. UBANDO

Department of Science and Technology-Industrial Technology Development Institute DOST Compound, Gen. Santos Avenue, Bicutan, Taguig City, Metro Manila, 1632, Philippines
* Tel.: 632-837-0032 fax: 632-837-0032

* E-mail: bsebarvia@yahoo.com


Received: 28 March 2018 /Accepted: 28 May 2018 /Published: 31 May 2018

Digital Sensors and Sensor Sysstems


Abstract: Molecularly imprinted polymer (MIP) for tetracycline was prepared via precipitation polymerization at 60°C for 24 h using methacrylic acid as the monomer, trimethylolpropane methacrylate (TRIM) as the crosslinker, 2,2-azobis–isobutyronitrile as initiator, dichloromethane as porogen and tertracycline HCl as template. After template-removal by methanol-acetic acid solvent extraction, the MIP suspension was coated as sensing layer of a piezoelectric quartz crystal transducer. The molecular recognition of tetracycline in the MIP coating was indicated by a corresponding frequency shift of the sensor response. The sensor response was optimized by varying the amount of coating and pH of solution measured. Different parameters like linearity (r=0.9921), sensitivity (41 Hz/ln [conc]), response time (2.4 min), and dynamic range of solutions (1 ´ 10-6 to 1 ´ 10-3 µg/mL tetracycline) were obtained. A decrease in sensitivity and selectivity ratio was observed for oxy- tetracycline and chlortetracycline in the selectivity study done. Acceptable % recovery was observed for milk and honey matrices. The developed tetracycline sensor is a possible cheaper methodology for screening and quantitation of low levels of tetracycline in foods.


Keywords: Molecularly imprinted polymer, Tetracycline, Piezoelectric quartz crystal sensor.


Acrobat reader logo Click <here> or title of paper to download the full pages article in pdf format



This work is licensed under a Creative Commons 4.0 International License


 Creative Commons License


Read more about Chemical Sensors






1999 - 2018 Copyright ©, International Frequency Sensor Association (IFSA) Publishing, S.L. All Rights Reserved.

Home - News - Links - Archives - Tools - Voltage-to-Frequency Converters - Standardization - Patents - Marketplace - Projects - Wish List - e-Shop - Sensor Jobs - Membership - Videos - Publishing - Site Map - Subscribe - Search

 Members Area -Sensors Portal -Training Courses - S&T Digest - For advertisers - Bookstore - Forums - Polls - Submit Press Release - Submit White Paper - Testimonies - Twitter - Facebook - LinkedIn