Sensors & Transducers



Vol. 253, Issue 6, November 2021, pp. 9-17





1, * Tatiana KUCHMENKO, 1, 2 Ruslan UMARKHANOV, 1 Anastasiia SHUBA and 3 Dariya MENZHULINA



1 Voronezh State University of Engineering Technologies, 19 Revolution Avenue, 394039 Voronezh, Russia

2 LLC “Sensorika – Novye Technologii”, 19 Revolution Avenue, apt. 1, 394039 Voronezh, Russia

3 Voronezh Children’s Clinical Hospital named after N. N. Burdenko 16 lane Health, Voronezh, Russia

Tel.: +7(473)255-42-67, fax: +7(473)255-42-67

E-mail: tak1907@mail.ru



Received: 25 October 2021 /Accepted: 25 November 2021 /Published: 30 November 2021





Abstract: The paper investigates the properties of gas sensors based on biohydroxyapatite for diagnostic the state of the upper respiratory tract of calves and humans. The process of synthesis of biohydroxyapatite of different mass is described. The peculiarities of sorption of volatile compounds on this sorbent depending on mass are considered for two modes of measurement (injection and frontal). The effectiveness and selectiveness of organic vapor microweighting using biohydroxyapatite phases of different mass are estimated. Possibilities of volatile organic compounds vapors identification in a mixture without separation are considered. For this task, the new parameters are calculated by the signals of one or two piezoelectric sensors with biohydroxyapatite of different masses. Results of analysis and identification of substances in the gas phase over nasal secretions of calves and humans with various respiratory diseases are presented. The intervals of the values of the calculated parameters are determined for reliable selection of samples into the “inflammation” group. The first and second order errors have been estimated in binary classification into groups “healthy” and “inflammation”. The minimum number of false-positive responses in the classification of samples is achieved using the parameters of two sensors with a biohydroxyapatite of different masses.


Keywords: Sensors, Biohydroxyapatite, Sorption, Volatile organic compounds, Diagnostics, Upper respiratory tract, Inflammation, Nasal secretion.

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